22 Best Endpoint Protection Software Of 2025

Deel IT is a global-first IT solution that helps you manage and automate your company's IT operations across more than 130 countries. It streamlines equipment and software management, making tasks like onboarding and offboarding straightforward, no matter where your team members are located.

Why I picked Deel IT: I chose Deel IT because of its integrated mobile device management (MDM) and endpoint protection features. These tools allow you to automatically secure devices by configuring them with necessary security measures and business-critical applications before they're delivered to your employees. This approach reduces risks associated with manual setups and ensures that devices are ready for immediate use upon arrival. 

Deel IT Standout Features & Integrations:

Features include the ability to grant and revoke application access remotely. This means you can control who has access to specific software and data, enhancing your organization's security posture. It also offers device lifecycle management, which covers everything from purchasing and provisioning to monitoring and recovering assets remotely. 

Integrations include Hubstaff, QuickBooks, Google Workspace, Slack, JIRA, Brex, Dropbox, Microsoft 365, SAP S/4HANA, Airtable, Google Sheets, and HubSpot.

Malwarebytes is an endpoint antivirus software that scans and removes malicious software, such as viruses, adware, and spyware. It operates in batch mode, which minimizes interference when other on-demand antimalware software is running on the computer.

Why I picked Malwarebytes Endpoint Protection: I chose Malwarebytes Endpoint Protection because it offers solid protection and functionality at a price point that works for budget-conscious startups. I found its malware protection was good, with a lightweight agent and straightforward interface

Malwarebytes Endpoint Protection Standout Features & Integrations:

Features I found are simple yet effective for startup endpoints. It provides essential features such as virus protection and file quarantine, making it a reliable and straightforward antivirus product.

Integrations are built around a range of native plug-ins developed in collaboration with industry leaders such as IBM, Microsoft, Splunk, ArcSight, and Kaseya.

Heimdal Threat Protection Endpoint is a cybersecurity suite that offers integrated protection for your business. It combines threat prevention, patching, antivirus, DNS traffic filtering, vulnerability management, access governance, and incident response for integrated protection of your business.

Why I picked Heimdal Threat Protection Endpoint: I picked Heimdal Threat Protection Endpoint for its integrated security solution, which combines multiple applications like antivirus, firewall, intrusion detection, and more. With machine learning capabilities, Heimdal detects and defends against various polymorphic malware threats.

Heimdal Threat Protection Endpoint Standout Features & Integrations:

Features that I thought stood out are the unified suite of features, including endpoint activity tracking through data analytics. It allows cybersecurity teams to respond quickly to incidents and provides actionable guidance through threat intelligence capabilities.

Integrations are provided via native integrations and include Adobe Acrobat Reader, Logitech, Skype, NGINX, and FileZilla.

Bitdefender GravityZone is a cloud-based cybersecurity application for workplace devices. It defends against viruses, malware, and other threats.

Why I picked Bitdefender GravityZone: I picked Bitdefender GravityZone for its strong security and user-friendly management. I felt it was a great choice of cybersecurity tool for small-to-medium-sized businesses due to its ease of use, allowing businesses to focus on core activities without the need for dedicated specialists.

Bitdefender GravityZone Standout Features & Integrations:

Features I believe that stood out include a single, user-friendly platform that supports various devices such as desktops, laptops, and physical devices. It employs machine learning and behavioral analysis for advanced threat detection, and can be used through cloud or on-prem management consoles.

Integrations rely on API keys from Bitdefender GravityZone to operate and include pre-built plug-ins such as Amazon AWS, Microsoft Active Directory, and ConnectWise Automate to give control over agent and agentless devices.

Avast Small Business Solutions is an endpoint security and antivirus software specifically tailored for small businesses. It offers next-gen endpoint protection tools (exploit mitigation, behavioral analysis, and ML) alongside antivirus, patch management, VPN, and USB protection features.

Why I picked Avast Small Business Solutions: I picked Avast Small Business Solutions because it is affordable and easy to use. It provides small businesses with automatic protection against cyber threats by monitoring and eliminating them centrally at each endpoint.

Avast Small Business Solutions Standout Features & Integrations:

Features I appreciated most are those tailored for small businesses, such as offering simplified endpoint protection through a single-screen interface.They enable cybersecurity teams to monitor potential viruses and detect suspicious files on devices both in the office and remotely.

Integrations are native and can be added by ClientID and Client Secret parameters via Avast Business Hub. Integrations include ConnectWise, ConnectWise Automate, and Ivanti.

ESET Endpoint Security safeguards company devices from cyber attacks using multiple layers of protection, global threat detection, and machine learning. It also benefits from human expertise and provides remediation options when needed.

Why I picked ESET Endpoint Security: I chose ESET Endpoint Security for its comprehensive malware detection and protection. ESET's Network Attack Protection shields your systems from ransomware by blocking network-level exploits that could lead to system infections. Eset has been top rated for accuracy and detection, which gave me confidence in its protection capabilities.

ESET Endpoint Security Standout Features & Integrations:

Features that caught my eye for endpoints are customizable options and automatic threat detection, ensuring secure devices for uninterrupted work. With cloud-powered scanning and minimal data transfer, you get accurate virus detection without compromising confidentiality or performance..

Integrations are built-in and include ConnectWise Automate, Datto, N-able, and NinjaOne.

Apex One is an endpoint security solution that proactively protects against vulnerabilities by virtually patching them. It scans for vulnerabilities based on criteria such as severity and Common Vulnerabilities and Exposures (CVE) listing, providing comprehensive protection for platforms and devices.

Why I picked Apex One: I chose Apex One because it utilizes deep scanning to detect malware, viruses, and other threats on all endpoints. It also collects data from millions of application events to identify and track potential risks, ensuring your product and systems are kept up-to-date with the latest cyber threats.

Apex One Standout Features & Integrations:

Features I found beneficial for endpoint protection and scanning include advanced threat techniques like machine learning, as well as noise-canceling methods such as census and safelisting. This combination minimizes false positives and enhances overall security.

Integrations consist of native plug-ins that enhance security visibility and functionality. Some of the popular plug-ins are IBM QRadar, Fortinet, and Splunk.

Cynet 360 is a complete endpoint security platform that uses AI and automation to protect your devices and analyze user behavior. It secures many different parts of your tech stack like computers, servers, and online services, ensuring comprehensive security for your environment.

Why I picked Cynet 360: I picked Cynet 360 for its all-in-one solution, combining endpoint management, antivirus protection, and threat intelligence all within a single application. It's perfect for small and medium-sized businesses seeking a comprehensive security platform.

Cynet 360 Standout Features & Integrations:

Features that I found interesting on Cynet 360's platform include automating error identification and resolution in SaaS and Cloud applications, simplifying problem-solving. It also streamlines threat investigation and remediation, enhancing security operations.

Integrations on the platform require configuration but are primarily native. They include AWS S3, Active Directory, Datto, Datto Autodesk, and N-able.

Kaspersky Business is a security software solution that protects organizations with threat detection and preventing, and configurations to reduce attack surfaces. It offers features like File, Mail, and Web Protection, machine learning analysis, and control over device, web, and application usage.

Why I picked Kaspersky Business: I picked Kaspersky Business for its adaptive protection. Its robust suite of tools struck me as a good fit for medium-sized and scaling business. With automated vulnerability and encryption management, you can proactively detect and mitigate threats.

Kaspersky Business Standout Features & Integrations:

Features I liked the most include a multi-layered protection approach based on AI algorithms and threat analysis. Kaspersky's AI automates manual tasks, freeing up your security teams to focus on critical tasks.

Integrations include native plug-ins such as ConnectWise Manage, Autotask, Tigerpaw, and SolarWinds N-central.

The Trellix Endpoint Protection Platform is a cybersecurity solution that protects devices and endpoints on your network. It uses advanced analytics, machine learning, and integration with other vendors' products to enhance your defense against evolving threats.

Why I picked Trellix Endpoint Protection Platform: I picked Trellix Endpoint Protection Platform because it lets companies bring all their security together in one place, in the cloud. Whether you're using mobile phones, computers, or other devices, Trellix's centralized management makes it easy to see what's going on and keeps things running smoothly.

Trellix Endpoint Protection Platform Standout Features & Integrations:

Features I liked in Trellix include behavior classification, driven by machine learning, to provide timely threat intelligence, such as fast identification of zero-day threats. I also like the unified dashboard, as well as the integrated anti-malware and firewall features.

Integrations that Trellix provides natively include Aruba ClearPass, BASEL II, Database Content Pack, and DNS Content Pack.